Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693372 | 0.93 | KAT2B (0.53) | ALDH1A1SMN1; SMN2POLBKAT2BKMT2A | |
| SCHEMBL9878203 | 0.89 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2POLBKAT2BKMT2A | |
| SCHEMBL10597376 | 0.86 | KMT2A (0.45) | ALDH1A1SMN1; SMN2POLBKAT2BKMT2A | |
| SCHEMBL10692288 | 0.82 | POLB (0.44) | ALDH1A1SMN1; SMN2POLBKMT2ATDP1 | |
| SCHEMBL10351576 | 0.82 | KAT2B (0.54) | ALDH1A1SMN1; SMN2POLBKAT2BKMT2A | |
| SCHEMBL10538157 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBKAT2BKMT2A | |
| SCHEMBL10597296 | 0.81 | POLB (0.45) | ALDH1A1SMN1; SMN2POLBKAT2BKMT2A | |
| SCHEMBL10692797 | 0.81 | RAPGEF4 (0.41) | ALDH1A1POLBKMT2ATDP1NT5E | |
| SCHEMBL29597632 | 0.80 | KMT2A (0.58) | ALDH1A1SMN1; SMN2POLBKMT2ATSHR | |
| SCHEMBL9877922 | 0.80 | KMT2A (0.58) | ALDH1A1SMN1; SMN2POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |