Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | EEF2K | O00418 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30861628 | 0.89 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL2363298 | 0.77 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL30861636 | 0.77 | POLB (0.72) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL6892551 | 0.77 | POLB (0.72) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| Water SCHEMBL3871916 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL30861620 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL11837932 | 0.73 | POLB (0.52) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL9634360 | 0.73 | CDC7 (0.49) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL30861654 | 0.73 | GAA (0.55) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL7127076 | 0.70 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485419-A1 | ACRIDINE DERIVATIVES | Trifree Limited (GB) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001974-A1 | ACRIDINE DERIVATIVES | TRIFREE LIMITED (GB) | 1991-02-21 | — | — | WO | disclosed |