Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | EEF2K | O00418 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892551 | 0.74 | POLB (0.72) | ACHEKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2363298 | 0.74 | ALDH1A1 (0.72) | CDC7EEF2KPLK4DYRK3PRKD3 | |
| SCHEMBL30861636 | 0.74 | POLB (0.72) | ACHEKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL30861628 | 0.73 | ALDH1A1 (0.65) | ACHEKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9634987 | 0.73 | ALDH1A1 (0.54) | CDC7EEF2KPLK4DYRK3PRKD3 | |
| Water SCHEMBL3871916 | 0.73 | ALDH1A1 (0.70) | CDC7EEF2KPLK4DYRK3PRKD3 | |
| SCHEMBL30861620 | 0.73 | ALDH1A1 (0.70) | CDC7EEF2KPLK4DYRK3PRKD3 | |
| SCHEMBL10286447 | 0.72 | ACHE (0.44) | ACHEKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL15491436 | 0.71 | DHODH (0.58) | CDC7EEF2KPLK4DYRK3PRKD3 | |
| SCHEMBL10620451 | 0.70 | ACHE (0.61) | ACHEKDM4EALDH1A1TSHRCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991001974-A1 | ACRIDINE DERIVATIVES | TRIFREE LIMITED (GB) | 1991-02-21 | — | — | WO | claimed |
| EP-0485419-A1 | ACRIDINE DERIVATIVES | Trifree Limited (GB) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001974-A1 | ACRIDINE DERIVATIVES | TRIFREE LIMITED (GB) | 1991-02-21 | — | — | WO | disclosed |