Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905336 | 0.81 | KDM4E (0.41) | KDM4EPSMB1PSMB5PSMB2SMN1; SMN2 | |
| SCHEMBL13475860 | 0.74 | SMN1; SMN2 (0.53) | KDM4EPSMB1PSMB5PSMB2SMN1; SMN2 | |
| SCHEMBL6333576 | 0.74 | LTA4H (0.52) | KDM4EPSMB1PSMB5PSMB2SMN1; SMN2 | |
| SCHEMBL9635130 | 0.73 | TSHR (0.41) | SMN1; SMN2CYP3A4HRH3MEN1KMT2A | |
| SCHEMBL1456663 | 0.73 | THRA (0.45) | KDM4EPSMB1PSMB5PSMB2SMN1; SMN2 | |
| SCHEMBL4254052 | 0.72 | SMN1; SMN2 (0.68) | KDM4EPSMB1PSMB5PSMB2SMN1; SMN2 | |
| SCHEMBL9635109 | 0.71 | PPARG (0.36) | — | |
| SCHEMBL17029438 | 0.71 | HDAC3 (0.47) | KDM4EPSMB1PSMB5PSMB2SMN1; SMN2 | |
| SCHEMBL8225106 | 0.70 | NR5A1 (0.58) | — | |
| SCHEMBL19912050 | 0.70 | CYP3A4 (0.56) | KDM4EPSMB1PSMB5PSMB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102966-A | Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |