Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687058 | 0.95 | SLC6A9 (0.57) | SLC6A9ALDH1A1TP53MEN1TSHR | |
| SCHEMBL9634663 | 0.94 | SLC6A9 (0.56) | SLC6A9ALDH1A1TP53MEN1TSHR | |
| SCHEMBL9635855 | 0.90 | SLC6A9 (0.64) | SLC6A9ALDH1A1TP53MEN1TSHR | |
| Fumaric Acid SCHEMBL9636082 | 0.87 | SLC6A9 (0.52) | SLC6A9ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL9687018 | 0.87 | SLC6A9 (0.60) | SLC6A9ALDH1A1MEN1TSHRKMT2A | |
| Fumaric Acid SCHEMBL9634756 | 0.86 | SLC6A9 (0.51) | SLC6A9ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL9685805 | 0.84 | SLC6A9 (0.61) | SLC6A9ALDH1A1TP53MEN1TSHR | |
| SCHEMBL9686403 | 0.83 | SLC6A9 (0.60) | SLC6A9ALDH1A1TP53MEN1TSHR | |
| SCHEMBL9634679 | 0.83 | SLC6A9 (0.54) | SLC6A9ALDH1A1TP53KMT2AHRH1 | |
| Fumaric Acid SCHEMBL9634770 | 0.83 | SLC6A9 (0.58) | SLC6A9TP53MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| US-5086056-A | Treating allergic diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-04 | — | — | US | disclosed |
| US-5011842-A | Antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-30 | — | — | US | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |