Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 5/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.47 |
| ▸ | PRKCB | P05771 | 4/20 | 0.47 |
| ▸ | PRKCA | P17252 | 4/20 | 0.47 |
| ▸ | PRKCH | P24723 | 4/20 | 0.47 |
| ▸ | PRKCI | P41743 | 4/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 5/20 | 0.46 |
| ▸ | PRKACG | P22612 | 4/20 | 0.46 |
| ▸ | PRKACB | P22694 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483344 | 0.82 | PRKACA (0.63) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL9635145 | 0.81 | PRKCG (0.52) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL9483093 | 0.77 | PRKACA (0.54) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL5000637 | 0.74 | PRKD3 (0.63) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL17737346 | 0.72 | MEN1 (0.60) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL10983368 | 0.70 | PRKCG (0.73) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL14094514 | 0.69 | PRKACA (0.75) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL10978592 | 0.69 | PRKCG (0.70) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL9541290 | 0.68 | PRKCG (0.86) | PRKCGPRKCZPRKCDPRKD3PRKCB | |
| SCHEMBL115053 | 0.67 | CYP3A4 (0.56) | PRKCGPRKCZPRKCDPRKD3PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |