Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19051706 | 0.77 | POLB (0.70) | POLBL3MBTL1GAAKMT2AALDH1A1 | |
| SCHEMBL13007126 | 0.77 | L3MBTL1 (0.61) | TSHRPOLBL3MBTL1GAAKMT2A | |
| SCHEMBL6274848 | 0.76 | CHRNB2 (0.50) | POLBL3MBTL1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL6324442 | 0.76 | CHRNA7 (0.47) | POLBGAAKMT2AMEN1LMNA | |
| SCHEMBL12794229 | 0.76 | GAA (0.73) | TSHRPOLBGAAKMT2AALDH1A1 | |
| SCHEMBL12207380 | 0.75 | CYP2C9 (0.57) | POLBL3MBTL1GAAKMT2AALDH1A1 | |
| SCHEMBL1711174 | 0.71 | CYP2C9 (0.45) | POLBL3MBTL1GAAKMT2AALDH1A1 | |
| SCHEMBL17294972 | 0.70 | CYP2C9 (0.52) | POLBL3MBTL1GAAKMT2AALDH1A1 | |
| SCHEMBL17304912 | 0.70 | CYP2C9 (0.52) | POLBL3MBTL1GAAKMT2AALDH1A1 | |
| SCHEMBL6319408 | 0.70 | CHRNB2 (0.61) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110933-A | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5084572-A | Cardiovascular disorders | BOARD OF REGENTS OF OKLAHOMA STATE UNIVERSITY (US) | 1992-01-28 | — | — | US | disclosed |