Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12240334 | 0.79 | KDM4E (0.45) | TSHRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9635275 | 0.78 | TSHR (0.37) | TSHRL3MBTL1ALDH1A1HPGDMEN1 | |
| SCHEMBL29624092 | 0.76 | TSHR (0.49) | TSHRL3MBTL1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9636467 | 0.74 | POLB (0.40) | TSHRL3MBTL1ALDH1A1HPGDMEN1 | |
| SCHEMBL14048753 | 0.74 | MEN1 (0.56) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL1708834 | 0.73 | TSHR (0.44) | TSHRL3MBTL1ALDH1A1HPGDPOLB | |
| SCHEMBL10723275 | 0.73 | ACHE (0.48) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL9143961 | 0.71 | ALDH1A1 (0.41) | TSHRALDH1A1HPGDPOLBMAPT | |
| SCHEMBL12203700 | 0.69 | TSHR (1.00) | TSHRMEN1KMT2AMAPTBRD4 | |
| SCHEMBL9835232 | 0.69 | MAPT (0.36) | L3MBTL1ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |