Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 3/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10894182 | 0.98 | ANPEP (0.38) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL16510462 | 0.78 | S100A4 (0.36) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL9094355 | 0.77 | S100A4 (0.35) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL68883 | 0.77 | HPGD (0.37) | MAPTLMNAS100A4TDP1MEN1 | |
| SCHEMBL10723275 | 0.77 | ACHE (0.48) | MAPTS100A4TDP1MEN1POLB | |
| Hydrochloric Acid SCHEMBL10916075 | 0.74 | ALDH1A1 (0.34) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL15035240 | 0.73 | S100A4 (0.36) | MAPTLMNAHTR2BS100A4TDP1 | |
| SCHEMBL11131924 | 0.72 | LMNA (0.45) | MAPTLMNAHTR2BACHEHPGD | |
| SCHEMBL11637916 | 0.72 | KDM4E (0.36) | MAPTLMNACYP1A2HTR2BMEN1 | |
| SCHEMBL8144693 | 0.71 | HTR2A (0.41) | MAPTANPEPTDP1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161218-B1 | BENZO-(PYRANO AND THIOPYRANO)PYRIDINES | CIBA-GEIGY AG (CH) | 1991-06-26 | — | — | EP | disclosed |
| EP-0161218-A2 | Benzo-(pyrano and thiopyrano)pyridines | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |