Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635409 | 0.94 | HTR7 (0.54) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636997 | 0.85 | HTR7 (0.53) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636871 | 0.82 | HTR7 (0.49) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636875 | 0.79 | HTR7 (0.56) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636903 | 0.79 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636870 | 0.79 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9636951 | 0.78 | ACHE (0.55) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635344 | 0.77 | HTR1A (0.49) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635370 | 0.76 | HTR7 (0.55) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL9635366 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |