Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11231689 | 0.99 | KDM1A (0.43) | KDM1AHTR2CHTR2BSLC6A4HTR2A | |
| SCHEMBL11231388 | 0.82 | HTR2C (0.52) | KDM1AHTR2CHTR2BSLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL11242374 | 0.81 | HTR2C (0.51) | KDM1AHTR2CHTR2BSLC6A4HTR2A | |
| SCHEMBL9635463 | 0.78 | HTR6 (0.46) | KDM1AHTR2CHTR2BSLC6A4HTR2A | |
| SCHEMBL11235803 | 0.73 | HTR2C (0.50) | HTR2C | |
| SCHEMBL11228929 | 0.72 | MAOA (0.48) | KDM1A | |
| Hydrochloric Acid SCHEMBL11226657 | 0.72 | HTR2C (0.49) | HTR2C | |
| SCHEMBL12131300 | 0.71 | PDE4B (0.37) | HTR2CHTR2BSLC6A4DRD2DRD1 | |
| SCHEMBL31028088 | 0.71 | ESR1 (0.39) | HTR2CHTR2BSLC6A4DRD2DRD1 | |
| SCHEMBL409985 | 0.70 | ACHE (0.43) | HTR2CHTR2BSLC6A4HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |