Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723823 | 0.87 | NOTUM (0.40) | ALDH1A1AKR1C3ALOX15KMT2ACYP2C9 | |
| SCHEMBL31342301 | 0.86 | AKR1C3 (0.50) | ALDH1A1AKR1C3ALOX15CDC25BATM | |
| SCHEMBL11245998 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1AKR1C3ALOX15KMT2ACYP3A4 | |
| SCHEMBL11402284 | 0.73 | ALDH1A1 (0.82) | ALDH1A1AKR1C3ALOX15KMT2ACYP3A4 | |
| SCHEMBL809436 | 0.73 | ALDH1A1 (0.82) | ALDH1A1AKR1C3ALOX15KMT2ACYP3A4 | |
| SCHEMBL29977835 | 0.73 | ALDH1A1 (0.82) | ALDH1A1AKR1C3ALOX15KMT2ACYP3A4 | |
| SCHEMBL28554392 | 0.73 | KDM4E (0.44) | ALDH1A1ALOX15KMT2AHSD17B10 | |
| Phthalic Acid SCHEMBL30575217 | 0.71 | ALDH1A1 (0.88) | ALDH1A1AKR1C3ALOX15KMT2ACYP3A4 | |
| Phthalic Acid SCHEMBL4396104 | 0.71 | ALDH1A1 (0.88) | ALDH1A1AKR1C3ALOX15KMT2ACYP3A4 | |
| Phthalic Acid SCHEMBL4797005 | 0.71 | ALDH1A1 (0.88) | ALDH1A1AKR1C3ALOX15KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149823-A | Sulfonamide substituted spirodilactams | SHELL OIL COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| US-5145910-A | Ketocarboxylated polymers | SHELL OIL COMPANY (US) | 1992-09-08 | — | — | US | disclosed |
| US-5112938-A | CYANO- AND CARBOXY-SUBSTITUTED SPIRODILACTAMS | SHELL OIL COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5103001-A | SPIRODILACTAMS | SHELL OIL COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-5093465-A | Polyamide containing spirodilactam moieties | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5093499-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-5061780-A | Poly(ether-bis-imide-spiro dilactam) polymer | SHELL OIL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-5037948-A | Cyano- and carboxy-substituted spirodilactams | SHELL OIL COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| US-5034504-A | Spirodilactam polyamide polymer | SHELL OIL COMPANY (US) | 1991-07-23 | — | — | US | disclosed |
| US-5028688-A | Polyamideimide polymers | SHELL OIL COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| US-4978736-A | Polyamideimide polymers | SHELL OIL COMPANY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4968812-A | Spirolactonelactams | SHELL OIL COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4968770-A | Polyamide from spirodilactam precursor and primary diamine | SHELL OIL COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4939251-A | Novel spirolactones | SHELL OIL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4927906-A | Novel polyamideimide polymers | SHELL OIL COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4914176-A | Poly(heterocyclic) polymers | SHELL OIL COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4908458-A | 1,5-Di(benzoheterocyclic)-3-oxopentane derivatives | SHELL OIL COMPANY (US) | 1990-03-13 | — | — | US | disclosed |