SCHEMBL9635845

SCHEMBL9635845

[CH2]C(C)c1ccccc1C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
CA2 P00918 2/20 0.39
CYP3A4 P08684 3/20 0.36
CYP2C19 P33261 2/20 0.36
GABRA1 P14867 3/20 0.34
GABRB2 P47870 3/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
KIF11 P52732 1/20 0.33
ATM Q13315 1/20 0.33
P2RX7 Q99572 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 1/20 0.31
FAAH O00519 1/20 0.30
CA1 P00915 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
GABRB1 P18505 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414888 0.81 GABRA1 (0.46) TSHRALDH1A1TDP1CA2CYP3A4
SCHEMBL4667743 0.81 GABRA1 (0.46) TSHRALDH1A1TDP1CA2CYP3A4
SCHEMBL9621326 0.81 TSHR (0.46) TSHRALDH1A1TDP1CA2CYP3A4
SCHEMBL8429801 0.80 P2RX7 (0.47) ALDH1A1TDP1P2RX7
SCHEMBL24816452 0.77 TSHR (0.43) TSHRALDH1A1TDP1CA2CYP3A4
Hydrogen Peroxide SCHEMBL49977 0.77 GABRA1 (0.48) TSHRALDH1A1TDP1CA2CYP3A4
SCHEMBL18367695 0.77 TSHR (0.43) TSHRALDH1A1TDP1CA2CYP3A4
SCHEMBL6055359 0.77 ALDH1A1 (0.48) TSHRALDH1A1TDP1CA2CYP3A4
SCHEMBL13907322 0.77 ALDH1A1 (0.48) TSHRALDH1A1TDP1CA2CYP3A4
SCHEMBL8274423 0.77 ALDH1A1 (0.48) TSHRALDH1A1TDP1CA2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171328-A Polypiperidinyl derivatives; light, oxygen and heat resistance BASF AKTIENGESELLSCHAFT (DE) 1992-12-15 US disclosed