Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167411 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL899595 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| SCHEMBL4601562 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL7036128 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL473081 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HDAC8DAPK3 | |
| SCHEMBL7639 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1HDAC8DAPK3 | |
| SCHEMBL3859558 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL2167277 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| SCHEMBL23493481 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8DAPK3 | |
| SCHEMBL2904668 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118723-A | Havig a high methacrylate content; surface releasing coating for temporary protection of adhesive | SHIN-ETSU CHEMICAL COMPANY, LIMITED (JP) | 1992-06-02 | — | — | US | disclosed |