SCHEMBL4601562

SCHEMBL4601562

C=Cc1ccc([Si](C)(C)Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.40
HDAC8 Q9BY41 3/20 0.39
TDP1 Q9NUW8 3/20 0.35
TP53 P04637 2/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.31
MDM2 Q00987 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899595 0.86 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL9636010 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL2167411 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL141101 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL7649599 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL705667 0.79 ALDH1A1 (0.36) ALDH1A1
SCHEMBL9488658 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL8758099 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL30991325 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL30423535 0.76 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113563684-B Amphiphilic single-chain Janus composite nanoparticle and preparation method and application thereof 中国科学院化学研究所 2022-10-28 CN claimed
CN-113563684-A Amphiphilic single-chain Janus composite nano-particle and preparation method and application thereof 中国科学院化学研究所 2021-10-29 CN claimed
US-20060142500-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2006-06-29 US claimed
US-20050182191-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2005-08-18 US claimed
US-20040059075-A1 Styrene copolymer KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2004-03-25 US claimed
US-5428067-A Surface modified inorganic, organic or polymeric support, covelantly bonded to anchor group while polymerized mixture of monomers and initiator bonded to anchor, and filling the free space of pores MACHEREY, NAGEL & CO. (DE) 1995-06-27 US claimed
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-4134382-B1 HYDROGENATED CONJUGATED DIENE-BASED POLYMER, HYDROGENATED CONJUGATED DIENE-BASED POLYMER COMPOSITION, RUBBER COMPOSITION, AND METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE-BASED POLYMER ASAHI CHEMICAL IND (JP) 2025-05-07 EP disclosed
CN-119497723-A Conjugated diene polymer, molded article, method for producing conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2025-02-21 CN disclosed
CN-119462990-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2025-02-18 CN disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-12215179-B2 Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, oil extended conjugated diene-based polymer, rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
US-4996266-A Branched elastomeric and block copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-26 US disclosed
US-4906691-A Adhesive compositions made with condensed phase polymers and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-06 US disclosed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP disclosed
US-4857618-A ELASTOMERIC, ANIONIC COPOLYMERS; ORGANOMETALLIC CONDENSING AGENT; PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed
US-4857615-A Method of making condensed phase polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed
EP-0311430-A2 Condensed phase polymers, method of making same, and adhesive compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-12 EP disclosed
US-4770968-A INCORPORATED RELEASE AGENT XEROX CORPORATION (US) 1988-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 ALDH1A1 2948/4885TSHR 159/4885HDAC8 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.