SCHEMBL9636031

SCHEMBL9636031

C#CCOc1ccc(C=O)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.56
TRIM24 O15164 1/20 0.56
TRIM33 Q9UPN9 1/20 0.56
POLB P06746 1/20 0.49
MAPT P10636 1/20 0.49
CA12 O43570 6/20 0.45
CA4 P22748 6/20 0.45
CA9 Q16790 6/20 0.45
CA1 P00915 2/20 0.45
GSTP1 P09211 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
CYP1A1 P04798 2/20 0.40
CYP1A2 P05177 2/20 0.40
ERN1 O75460 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2024267 0.81 MAOB (0.45) CA12CA4CA9CA1GSTP1
SCHEMBL4638260 0.81 GSTP1 (0.45) CA12CA4CA9CA1GSTP1
SCHEMBL9634543 0.78 ALDH1A1 (0.63) TYRTRIM24TRIM33MAPTCA12
SCHEMBL1004413 0.78 TYR (0.66) TYRTRIM24TRIM33POLBMAPT
SCHEMBL29708063 0.78 TYR (0.66) TYRTRIM24TRIM33POLBMAPT
SCHEMBL28486841 0.78 TYR (0.61) TYRTRIM24TRIM33POLBMAPT
SCHEMBL19640150 0.77 HPGD (0.41) TYRTRIM24TRIM33GSTP1ALDH1A1
SCHEMBL14149542 0.77 MAOB (0.45) CA12CA4CA9CA1GSTP1
SCHEMBL15080749 0.77 KDM4E (0.52) CA12CA4CA9CA1GSTP1
SCHEMBL17848287 0.77 GSTP1 (0.42) POLBMAPTCA12CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121293265-A Cholesterol-salicylaldehyde conjugate, preparation method, application and N based on cholesterol-salicylaldehyde conjugate2H4And pH fluorescence analysis and gel response method 西安交通大学 2026-01-09 CN disclosed
US-11129909-B2 Conjugate and block copolymer containing fluorescent chromophore and preparation method therefor and use thereof UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2021-09-28 US disclosed
US-20200155707-A1 CONJUGATE AND BLOCK COPOLYMER CONTAINING FLUORESCENT CHROMOPHORE AND PREPARATION METHOD THEREFOR AND USE THEREOF UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2020-05-21 US disclosed
US-5104881-A 2-ARYLIMIDAZOPYRIDINES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-04-14 US disclosed
US-4654344-A ALSO AFFECT BLOOD PRESSURE AND MYOCARDIAL CONTRACTIONS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-03-31 US disclosed
US-4616090-A 2-arylimidazopyridines intermediates MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-10-07 US disclosed
EP-0072926-B1 2-ARYLIMIDAZOPYRIDINES MERCK PATENT GmbH (DE) 1986-09-24 EP disclosed
US-4575505-A Pharmaceutical compositions containing 2-aryltetraazaindenes for treating ulcers or cardiac insufficiency or blood pressure abnormalities MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-03-11 US disclosed
US-4477454-A INDOTROPIC AGENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-10-16 US disclosed
EP-0093951-A2 2-Aryl-tetraazaindenes MERCK PATENT GmbH (DE) 1983-11-16 EP disclosed
EP-0072926-A1 2-Arylimidazopyridines MERCK PATENT GmbH (DE) 1983-03-02 EP disclosed
US-4151291-A ANALGESICS UNICLER (FR) 1979-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11129909-B2 Conjugate and block copolymer containing fluorescent chromophore and preparation method therefor and use thereof WEE1, FAR1, FURIN TYR 1768/4885TRIM24 4068/4885TRIM33 3269/4885
US-20200155707-A1 CONJUGATE AND BLOCK COPOLYMER CONTAINING FLUORESCENT CHROMOPHORE AND PREPARATION METHOD THEREFOR AND USE THEREOF WEE1, FAR1, FURIN TYR 1768/4885TRIM24 4068/4885TRIM33 3269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.