Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9635000 | 0.92 | ALDH1A1 (0.40) | ALDH1A1TSHRMEN1KMT2ASLC6A9 | |
| SCHEMBL9687118 | 0.91 | MEN1 (0.42) | ALDH1A1TSHRMEN1KMT2ASLC6A9 | |
| SCHEMBL6151147 | 0.85 | MEN1 (0.58) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL9635883 | 0.85 | MEN1 (0.47) | ALDH1A1TSHRMEN1KMT2ASLC6A9 | |
| Fumaric Acid SCHEMBL9636370 | 0.83 | SLC6A9 (0.38) | ALDH1A1TSHRMEN1KMT2ASLC6A9 | |
| SCHEMBL6586477 | 0.82 | MEN1 (0.54) | ALDH1A1TSHRMEN1KMT2AHRH1 | |
| SCHEMBL9634434 | 0.79 | SLC6A9 (0.46) | ALDH1A1TSHRMEN1KMT2ASLC6A9 | |
| SCHEMBL9635855 | 0.78 | SLC6A9 (0.64) | ALDH1A1TSHRMEN1KMT2ASLC6A9 | |
| Fumaric Acid SCHEMBL10499414 | 0.77 | TSHR (0.51) | ALDH1A1TSHRMEN1KMT2APOLB | |
| Fumaric Acid SCHEMBL10499430 | 0.77 | TSHR (0.51) | ALDH1A1TSHRMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| US-5086056-A | Treating allergic diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-04 | — | — | US | disclosed |
| US-5011842-A | Antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-30 | — | — | US | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |
| EP-0307014-A1 | Anti-allergic 2-(heterocyclyl alkyl) imidazo pyridines and 2-(heterocyclyl alkyl) purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-03-15 | — | — | EP | disclosed |