Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18664157 | 0.72 | NOX1 (0.48) | L3MBTL1MAPTPOLBHPGDTDP1 | |
| SCHEMBL23018616 | 0.68 | L3MBTL1 (0.54) | L3MBTL1GSK3BMAPTPOLBHPGD | |
| SCHEMBL21375011 | 0.67 | L3MBTL1 (0.53) | L3MBTL1GSK3BMAPTPOLBHPGD | |
| SCHEMBL3194688 | 0.67 | L3MBTL1 (0.58) | L3MBTL1GSK3BMAPTPOLBHPGD | |
| SCHEMBL9636556 | 0.66 | ALDH1A1 (0.35) | MAPTTDP1HSD17B10ALDH1A1ACVR1 | |
| SCHEMBL4093743 | 0.66 | MAPT (0.64) | L3MBTL1GSK3BMAPTPOLBHPGD | |
| SCHEMBL8988 | 0.65 | L3MBTL1 (1.00) | L3MBTL1GSK3BMAPTPOLBHPGD | |
| Phthalimide SCHEMBL23063638 | 0.65 | GSK3B (0.88) | L3MBTL1GSK3BMAPTPOLBHPGD | |
| SCHEMBL23018613 | 0.65 | L3MBTL1 (0.58) | L3MBTL1MAPTPOLBHPGDTDP1 | |
| SCHEMBL23018540 | 0.65 | L3MBTL1 (0.58) | L3MBTL1MAPTPOLBHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |