Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510450 | 0.79 | OPRK1 (0.41) | NPC1RAB9AALDH1A1MAPTOPRK1 | |
| SCHEMBL9513581 | 0.78 | OPRK1 (0.36) | NPC1RAB9AALDH1A1MAPTOPRK1 | |
| SCHEMBL9510432 | 0.76 | OPRK1 (0.34) | NPC1RAB9AALDH1A1OPRK1SMN1; SMN2 | |
| SCHEMBL9511858 | 0.76 | OPRK1 (0.35) | NPC1RAB9AALDH1A1MAPTOPRK1 | |
| SCHEMBL9511866 | 0.75 | OPRK1 (0.34) | NPC1RAB9AALDH1A1OPRK1SMN1; SMN2 | |
| SCHEMBL2524058 | 0.74 | OPRK1 (0.58) | NPC1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL9636598 | 0.69 | HPGD (0.37) | NPC1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL3023952 | 0.67 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1MAPTGAA | |
| SCHEMBL9636497 | 0.66 | KDM4E (0.34) | NPC1RAB9AALDH1A1MAPTOPRK1 | |
| SCHEMBL9635225 | 0.66 | NPSR1 (0.32) | ALDH1A1GAAKDM4EHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0368063-A1 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |