Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513923 | 0.81 | BCL2L1 (0.31) | HPGDNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9513529 | 0.80 | MPO (0.37) | — | |
| SCHEMBL9513581 | 0.79 | OPRK1 (0.36) | OPRK1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL9636653 | 0.79 | NPC1 (0.41) | OPRK1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL9513959 | 0.78 | CTSL (0.36) | HPGDNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9511924 | 0.77 | ALOX5 (0.42) | HPGDNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL9510432 | 0.76 | OPRK1 (0.34) | OPRK1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL9511866 | 0.75 | OPRK1 (0.34) | OPRK1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL9512567 | 0.74 | KDM4E (0.43) | NPC1RAB9ARYR2KDM4E | |
| SCHEMBL9510505 | 0.74 | KDM4E (0.47) | NPC1RAB9AALDH1A1RYR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112194554-A | Preparation process and production process system of (o) p-chlorotoluene | 湖北山水化工有限公司 | 2021-01-08 | — | — | CN | claimed |
| JP-4211029-A | — | — | None | — | — | JP | disclosed |
| CN-115518402-B | Toluene chlorination liquid post-treatment device and treatment method | 中盐常州化工股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-113896612-B | Method for selectively preparing o-chlorotoluene | 常州新东化工发展有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-115518402-A | Toluene chlorination liquid post-treatment device and treatment method | 中盐常州化工股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-113896612-A | Method for selectively preparing o-chlorotoluene | 常州新东化工发展有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-112194554-A | Preparation process and production process system of (o) p-chlorotoluene | 湖北山水化工有限公司 | 2021-01-08 | — | — | CN | disclosed |
| EP-0442115-B1 | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1993-11-24 | — | — | EP | disclosed |
| JP-H04211029-A | RING-CHLORINCATION OF AROMATIC HYDROCARBON | BAYER AG | 1992-08-03 | — | — | JP | disclosed |
| US-5105036-A | Friedel-Crafts catalyst and oxy-substituted cyclic amidines as cocatylsts; preferential formation of p-isomer | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0442115-A1 | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1991-08-21 | — | — | EP | disclosed |