Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 3/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637718 | 0.82 | CRHR1 (0.37) | ALDH1A1KDM4ENQO2HPGDTSHR | |
| SCHEMBL7561913 | 0.80 | KDM4E (0.60) | ALDH1A1KDM4EMAPTMCL1L3MBTL1 | |
| SCHEMBL13084305 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTMCL1L3MBTL1 | |
| SCHEMBL9637797 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL18157885 | 0.73 | TDP1 (0.52) | ALDH1A1KDM4EMAPTMCL1L3MBTL1 | |
| SCHEMBL19534369 | 0.71 | GAA (0.40) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL1424667 | 0.69 | KDM4E (0.53) | ALDH1A1KDM4ESMN1; SMN2LMNAGAA | |
| SCHEMBL19514135 | 0.68 | MEN1 (0.48) | ALDH1A1KDM4ESMN1; SMN2LMNAGAA | |
| SCHEMBL26906287 | 0.68 | NQO2 (0.43) | ALDH1A1KDM4ESMN1; SMN2GAAMAPK1 | |
| SCHEMBL18839614 | 0.67 | NQO2 (0.39) | ALDH1A1KDM4ELMNAKMT2ANQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5094759-A | Method of water treatment using 2,6-substituted aminopyridines and polymer derived therefrom | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1992-03-10 | — | — | US | disclosed |
| US-5026802-A | Polymers derived from 2,6-substituted-4-amino-pyridines | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1991-06-25 | — | — | US | disclosed |
| US-4940796-A | 2,6-substituted-4-aminopyridines and their corresponding intermediates | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1990-07-10 | — | — | US | disclosed |