Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATF1 | P18846 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114046 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MALT1NQO2MAPTL3MBTL1 | |
| SCHEMBL9636673 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MALT1NQO2MAPTL3MBTL1 | |
| SCHEMBL31029421 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MALT1MAPTL3MBTL1KDM4E | |
| SCHEMBL19514135 | 0.76 | MEN1 (0.48) | ALDH1A1MALT1NQO2KDM4EGPBAR1 | |
| SCHEMBL26906287 | 0.76 | NQO2 (0.43) | ALDH1A1MALT1NQO2KDM4EGPBAR1 | |
| SCHEMBL621293 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MALT1MAPTL3MBTL1KDM4E | |
| SCHEMBL18839614 | 0.75 | NQO2 (0.39) | ALDH1A1MALT1NQO2KDM4EGPBAR1 | |
| SCHEMBL4574258 | 0.75 | MAPT (0.44) | ALDH1A1MAPTL3MBTL1KMT2ALMNA | |
| SCHEMBL1004039 | 0.73 | TPMT (0.52) | ALDH1A1MAPTGPBAR1HPGDHTT | |
| SCHEMBL3784787 | 0.73 | TPMT (0.46) | ALDH1A1MAPTGPBAR1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5094759-A | Method of water treatment using 2,6-substituted aminopyridines and polymer derived therefrom | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1992-03-10 | — | — | US | disclosed |
| US-5026802-A | Polymers derived from 2,6-substituted-4-amino-pyridines | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1991-06-25 | — | — | US | disclosed |
| US-4940796-A | 2,6-substituted-4-aminopyridines and their corresponding intermediates | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 1990-07-10 | — | — | US | disclosed |