Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003109 | 0.73 | L3MBTL1 (0.39) | P2RX7PLAUMKNK1MKNK2L3MBTL1 | |
| SCHEMBL9251633 | 0.72 | CYP2C9 (0.42) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10660840 | 0.71 | — | — | |
| SCHEMBL25991171 | 0.71 | PLAU (0.40) | P2RX7PLAUMKNK1MKNK2L3MBTL1 | |
| SCHEMBL24754894 | 0.70 | — | — | |
| SCHEMBL20920913 | 0.70 | — | — | |
| SCHEMBL2608518 | 0.70 | — | — | |
| SCHEMBL19673838 | 0.68 | NOS3 (0.40) | P2RX7PLAUMKNK1MKNK2L3MBTL1 | |
| SCHEMBL15233740 | 0.68 | PLAU (0.38) | P2RX7PLAUMKNK1MKNK2L3MBTL1 | |
| SCHEMBL1850348 | 0.67 | ADRA2A (0.48) | PLAUHSD17B10L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278411-B1 | GEL-TYPE CHELATING RESINS AND A PROCESS FOR REMOVAL OF MULTIVALENT, ALKALINE EARTH OR HEAVY METAL CATIONS FROM SOLUTIONS | THE DOW CHEMICAL COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |
| US-4895905-A | BEAD HAVING LESS CROSSLINKING AND MORE ELASTICITY IN THE SHELL THAN IN THE CORE; STRENGHT; REGENERATION; OSMOTIC SHOCK RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0278411-A2 | Gel-type chelating resins and a process for removal of multivalent, alkaline earth or heavy metal cations from solutions | THE DOW CHEMICAL COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |