SCHEMBL9636701

SCHEMBL9636701

CCCCCCCCCCOc1cc(O)ccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
SOAT1 P35610 1/20 0.50
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
PTPN11 Q06124 3/20 0.49
NR5A1 Q13285 1/20 0.49
ESR2 Q92731 1/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALOX5 P09917 1/20 0.46
CNR1 P21554 3/20 0.46
CNR2 P34972 3/20 0.46
CYSLTR2 Q9NS75 1/20 0.45
CYSLTR1 Q9Y271 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9224458 1.00 KDM4E (0.50) KDM4ESOAT1THRATHRBPTPN11
SCHEMBL9194402 1.00 KDM4E (0.50) KDM4ESOAT1THRATHRBPTPN11
SCHEMBL8880080 0.98 KDM4E (0.51) KDM4ESOAT1THRATHRBPTPN11
Methane SCHEMBL27790275 0.97 KDM4E (0.50) KDM4ESOAT1THRATHRBPTPN11
SCHEMBL5672495 0.87 SOAT1 (0.44) SOAT1THRATHRBPTPN11NR5A1
SCHEMBL9729977 0.84 THRA (0.45) KDM4ETHRATHRBPTPN11ALDH1A1
SCHEMBL7713999 0.84 THRA (0.53) KDM4ESOAT1THRATHRBPTPN11
SCHEMBL15574397 0.84 PTPN11 (0.56) SOAT1THRATHRBPTPN11
SCHEMBL4598873 0.83 PTPN11 (0.60) THRATHRBPTPN11ALDH1A1
SCHEMBL8769895 0.83 PTPN11 (0.60) THRATHRBPTPN11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0299789-B1 MESOMORPHIC COMPOUND HAVING ALKYL BETA-HYDROXYCARBOXYLATE AS CHIRAL GROUP AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME MITSUBISHI RAYON CO., LTD. (JP) 1992-05-20 EP disclosed
EP-0299789-A1 Mesomorphic compound having alkyl beta-hydroxycarboxylate as chiral group and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD. (JP) 1989-01-18 EP disclosed