Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.43 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729980 | 0.88 | KDM4E (0.47) | THRATHRBKDM4EALDH1A1PTPN11 | |
| SCHEMBL9194402 | 0.84 | KDM4E (0.50) | THRATHRBKDM4EALDH1A1PTPN11 | |
| SCHEMBL9636701 | 0.84 | KDM4E (0.50) | THRATHRBKDM4EALDH1A1PTPN11 | |
| SCHEMBL9224458 | 0.84 | KDM4E (0.50) | THRATHRBKDM4EALDH1A1PTPN11 | |
| SCHEMBL8880080 | 0.83 | KDM4E (0.51) | THRATHRBKDM4EALDH1A1PTPN11 | |
| Methane SCHEMBL27790275 | 0.82 | KDM4E (0.50) | THRATHRBKDM4EALDH1A1PTPN11 | |
| SCHEMBL4598873 | 0.77 | PTPN11 (0.60) | THRATHRBALDH1A1PTPN11 | |
| SCHEMBL8769895 | 0.77 | PTPN11 (0.60) | THRATHRBALDH1A1PTPN11 | |
| SCHEMBL8986588 | 0.77 | PTPN11 (0.60) | THRATHRBALDH1A1PTPN11 | |
| SCHEMBL10871798 | 0.77 | PTPN11 (0.60) | THRATHRBALDH1A1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5167863-A | Ferroelectricity; electrooptic switches | HITACHI, LTD. (JP) | 1992-12-01 | — | — | US | disclosed |