Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636828 | 0.81 | MAPT (0.32) | MAPTADRB2ALDH1A1MEN1USP2 | |
| SCHEMBL10623128 | 0.69 | MAPT (0.38) | MAPTATMALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL15019998 | 0.68 | RAB9A (0.46) | MAPTATMCDK5CDK5R1ALDH1A1 | |
| SCHEMBL9771695 | 0.65 | ATM (0.31) | ATMADRB2 | |
| SCHEMBL14118361 | 0.65 | RAB9A (0.43) | MAPTATMALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1815585 | 0.65 | RAB9A (0.49) | MAPTATMCDK5CDK5R1ALDH1A1 | |
| SCHEMBL5912889 | 0.65 | RAB9A (0.49) | MAPTATMCDK5CDK5R1ALDH1A1 | |
| SCHEMBL2045312 | 0.65 | HCAR3 (0.38) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4234259 | 0.64 | MEN1 (0.40) | MAPTALDH1A1MEN1USP2KMT2A | |
| SCHEMBL210588 | 0.62 | RAB9A (0.43) | MAPTATMCDK5CDK5R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489775-A1 | HAIR-DYEING PROCESS USING DIRECT DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-06-17 | — | — | EP | disclosed |
| WO-1991003231-A1 | HAIR-DYEING PROCESS USING DIRECT DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-03-21 | — | — | WO | disclosed |