Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636712 | 0.81 | MAPT (0.35) | MAPTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL4234259 | 0.79 | MEN1 (0.40) | MAPTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL688608 | 0.75 | TSHR (0.46) | MAPTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL15018382 | 0.68 | MAPT (0.36) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL27719080 | 0.67 | GAA (0.47) | MAPTMEN1USP2KMT2AKEAP1 | |
| SCHEMBL13276270 | 0.66 | LMNA (0.36) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL17919413 | 0.65 | GAA (0.48) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7001026 | 0.64 | CYP3A4 (0.56) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL1678371 | 0.64 | GPR35 (0.39) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL27832802 | 0.64 | MEN1 (0.53) | MAPTMEN1USP2KMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489775-A1 | HAIR-DYEING PROCESS USING DIRECT DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-06-17 | — | — | EP | disclosed |
| WO-1991003231-A1 | HAIR-DYEING PROCESS USING DIRECT DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-03-21 | — | — | WO | disclosed |