Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11182877 | 0.93 | KDM4E (0.53) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL9636784 | 0.90 | KDM4E (0.76) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL9635338 | 0.89 | KDM4E (0.58) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL6305606 | 0.87 | KDM4E (0.80) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| Hydrochloric Acid SCHEMBL10739298 | 0.86 | KDM4E (0.79) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL9686413 | 0.85 | STAT3 (0.47) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL5258333 | 0.84 | STAT3 (0.62) | KDM4EHPGDALDH1A1HSD17B10STAT3 | |
| SCHEMBL6776958 | 0.84 | ADRB2 (0.59) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL9633508 | 0.83 | KDM4E (0.58) | KDM4EHPGDALDH1A1HSD17B10PMP22 | |
| SCHEMBL11235862 | 0.82 | STAT3 (0.54) | KDM4EHPGDALDH1A1HSD17B10STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195135-B1 | A PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACID DERIVATIVES | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1992-06-17 | — | — | EP | disclosed |
| EP-0195135-A1 | A process for the preparation of quinoline carboxylic acid derivatives | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1986-09-24 | — | — | EP | disclosed |