Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.47 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911584 | 0.77 | FFAR1 (0.50) | FDPSALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4591759 | 0.77 | FFAR1 (0.50) | FDPSALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8166949 | 0.76 | MMP2 (0.50) | FDPSBTN3A1PDE3AALDH1A1RAB9A | |
| SCHEMBL10534062 | 0.75 | ALDH1A1 (0.51) | ALDH1A1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4681614 | 0.75 | — | — | |
| SCHEMBL4681609 | 0.75 | — | — | |
| SCHEMBL8429709 | 0.74 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| Hydrochloric Acid SCHEMBL27340547 | 0.74 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL11408451 | 0.73 | FFAR1 (0.62) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL4684825 | 0.72 | ALDH1A1 (0.45) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230068-B1 | USE OF A GEMINAL DIPHOSPHONIC ACID COMPOUND TO PREPARE A MEDICAMENT | Norwich Eaton Pharmaceuticals, Inc. (US) | 1992-07-15 | — | — | EP | claimed |