Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 9/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9636876 | 0.99 | GPR84 (0.60) | GPR84SLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL11050384 | 0.88 | MPO (0.55) | GPR84SLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL27584422 | 0.79 | GPR84 (0.61) | GPR84SLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL18383118 | 0.78 | GPR84 (1.00) | GPR84SLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL30482437 | 0.78 | GPR84 (1.00) | GPR84SLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL30913603 | 0.78 | GPR84 (1.00) | GPR84SLC6A4MPOHTR2ATRPM8 | |
| SCHEMBL2778860 | 0.74 | HTR6 (0.67) | SLC6A4HTR2AKMT2AMAPK1HTR2C | |
| SCHEMBL29007187 | 0.71 | GPR84 (1.00) | GPR84MPOHTR2ATRPM8HTR1A | |
| SCHEMBL5726056 | 0.70 | SLC6A4 (1.00) | GPR84SLC6A4MPOHTR2ATRPM8 | |
| Hydrochloric Acid SCHEMBL1574167 | 0.69 | HTR2C (0.43) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |