Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.50 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175866 | 0.94 | HSPA5 (0.50) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL3628725 | 0.83 | ALOX15 (0.68) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27742431 | 0.82 | ALOX15 (0.45) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16736796 | 0.82 | ALOX15 (0.48) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8670928 | 0.81 | ALDH1A1 (0.65) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9054498 | 0.80 | SMN1; SMN2 (0.56) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16736913 | 0.80 | SMN1; SMN2 (0.46) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16736855 | 0.80 | ALOX15 (0.46) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9154600 | 0.79 | ALOX15 (0.50) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12733114 | 0.78 | ALOX15 (0.68) | HSPA5ALOX15ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173562-A | Moldability, shrink resistance, oxidation resistance | CHISSO AMERICA INC. (US) | 1992-12-22 | — | — | US | disclosed |