Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.56 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.56 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628725 | 0.88 | ALOX15 (0.68) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL12733114 | 0.88 | ALOX15 (0.68) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL2931006 | 0.85 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL29405765 | 0.85 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL9008257 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL9175866 | 0.83 | HSPA5 (0.50) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL11682411 | 0.82 | BCL2 (0.55) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL27465722 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL9636859 | 0.80 | HSPA5 (0.52) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 | |
| SCHEMBL9154600 | 0.80 | ALOX15 (0.50) | SMN1; SMN2ALDH1A1ALOX15MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8283279-A | — | — | None | — | — | JP | disclosed |
| JP-H08283279-A | NEW CYCLIC PYROPHOSPHITE AND COMPOSITION STABILIZED THEREWITH | CIBA GEIGY AG | 1996-10-29 | — | — | JP | disclosed |