Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.39 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638021 | 0.91 | TDP1 (0.43) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL9636927 | 0.91 | TDP1 (0.42) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL9638063 | 0.90 | CTSB (0.46) | CTSBCTSKNT5EP2RY6P2RY14 | |
| SCHEMBL9638061 | 0.90 | CTSB (0.46) | CTSBCTSKNT5EP2RY6P2RY14 | |
| SCHEMBL10694865 | 0.88 | TDP1 (0.41) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL9637913 | 0.88 | TDP1 (0.41) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL9638270 | 0.85 | P2RY6 (0.50) | CTSBCTSKNT5EP2RY6P2RY14 | |
| SCHEMBL9638269 | 0.85 | P2RY6 (0.50) | CTSBCTSKNT5EP2RY6P2RY14 | |
| SCHEMBL11246189 | 0.85 | P2RY6 (0.50) | CTSBCTSKNT5EP2RY6P2RY14 | |
| SCHEMBL11246184 | 0.85 | P2RY6 (0.50) | CTSBCTSKNT5EP2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | disclosed |