Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784582 | 0.77 | CA1 (0.36) | — | |
| SCHEMBL20198348 | 0.76 | ACHE (0.38) | RAPGEF4ACHE | |
| SCHEMBL2788624 | 0.75 | TDP1 (0.43) | ACHETSHRSMN1; SMN2 | |
| SCHEMBL4127095 | 0.74 | HDAC1 (0.37) | PTGS2ACHETSHRSMN1; SMN2 | |
| SCHEMBL30176409 | 0.73 | — | — | |
| SCHEMBL1049725 | 0.73 | — | — | |
| SCHEMBL26934437 | 0.71 | CES2 (0.37) | ACHETSHR | |
| SCHEMBL24952545 | 0.71 | CES2 (0.36) | — | |
| SCHEMBL22199221 | 0.69 | HTR2A (0.44) | SMN1; SMN2 | |
| SCHEMBL20384374 | 0.69 | NFE2L2 (0.34) | PTGS2ACHEPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144004-A | Heat resistance, selective degradation, reaction of halogen substituted sulfones and sulfoxides and alkali metal sulfides | PHILLIPS PETROLEUM COMPANY (US) | 1992-09-01 | — | — | US | disclosed |