Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566040 | 0.86 | DPP4 (0.44) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL2740188 | 0.84 | DPP9 (0.42) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL9572307 | 0.83 | SLC7A5 (0.40) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL1031751 | 0.80 | PAX8 (0.47) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL9637257 | 0.80 | ACE (0.53) | MMEACECPA1ACE2CTRB1 | |
| SCHEMBL24581091 | 0.79 | PAX8 (0.50) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL29160549 | 0.79 | ALDH1A1 (0.40) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL1657595 | 0.79 | ALDH1A1 (0.36) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL9638304 | 0.78 | DPP7 (0.50) | DPP4DPP8DPP7SLC15A1DPP9 | |
| SCHEMBL7306765 | 0.77 | CYP2C9 (0.41) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | claimed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | claimed |