SCHEMBL9572307

SCHEMBL9572307

CCC(C)C(C=O)NC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.40
LARS1 Q9P2J5 1/20 0.36
SCN9A Q15858 3/20 0.36
ANPEP P15144 2/20 0.35
RNPEP Q9H4A4 2/20 0.35
DNPEP Q9ULA0 1/20 0.35
AAK1 Q2M2I8 1/20 0.35
CTSD P07339 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
CTSK P43235 1/20 0.33
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
PAX8 Q06710 1/20 0.33
SLC15A1 P46059 1/20 0.33
MME P08473 1/20 0.33
ACE P12821 1/20 0.33
CPA1 P15085 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2740188 0.85 DPP9 (0.42) DPP4DPP8DPP9DPP7PAX8
SCHEMBL16566060 0.83 SLC7A5 (0.42) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL9637211 0.83 PAX8 (0.46) DPP4DPP8DPP9DPP7PAX8
SCHEMBL8270222 0.80 SLC7A5 (0.42) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL16566040 0.80 DPP4 (0.44) SLC7A5ANPEPDPP4DPP8DPP9
SCHEMBL9638304 0.79 DPP7 (0.50) DPP4DPP8DPP9DPP7SLC15A1
SCHEMBL20828058 0.78 ALDH1A1 (0.49) SCN9AANPEPCPA1ACE2
SCHEMBL25587465 0.78 SLC7A5 (0.47) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL8817388 0.76 CAPN1 (0.46) SLC7A5LARS1SCN9AANPEPRNPEP
SCHEMBL2475740 0.76 CAPN1 (0.46) SLC7A5LARS1SCN9AANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543310-A2 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1993-05-26 EP disclosed