SCHEMBL9637270

SCHEMBL9637270

CCOC(=O)NC(CC)CO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.46
LMNA P02545 6/20 0.41
CNR1 P21554 1/20 0.41
ADRA1A P35348 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ABCC3 O15438 1/20 0.40
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
HTT P42858 3/20 0.38
MAPK1 P28482 1/20 0.38
ALOX15 P16050 2/20 0.38
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.36
ATM Q13315 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810150 1.00 SMN1; SMN2 (0.46) SMN1; SMN2LMNACNR1ADRA1ATDP1
Acetic Acid SCHEMBL9638139 0.94 SMN1; SMN2 (0.42) SMN1; SMN2LMNACNR1ADRA1ATDP1
SCHEMBL15502152 0.91 GAA (0.42) SMN1; SMN2LMNACNR1ADRA1ATDP1
SCHEMBL12928698 0.89 SMN1; SMN2 (0.50) SMN1; SMN2LMNAMGAMGAASI
SCHEMBL12482529 0.83 TDP1 (0.44) SMN1; SMN2LMNACNR1ADRA1ATDP1
SCHEMBL8153834 0.82 SMN1; SMN2 (0.45) SMN1; SMN2LMNAMGAMGAASI
SCHEMBL27108524 0.82 TAS1R3 (0.45) SMN1; SMN2LMNAMGAMGAASI
SCHEMBL15502087 0.81 LMNA (0.45) SMN1; SMN2LMNATDP1KDM4EMGAM
SCHEMBL9058964 0.81 SMN1; SMN2 (0.41) SMN1; SMN2LMNAMGAMGAASI
SCHEMBL19343059 0.80 SMN1; SMN2 (0.47) SMN1; SMN2LMNACNR1ADRA1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264137-B1 A laundry detergent composition comprising glycosyl hydrolase PROCTER & GAMBLE (US) 2016-02-10 EP disclosed
EP-0239122-B1 PROCESS FOR THE ENZYMATIC RESOLUTION OF RACEMIC 2-AMINO-1-ALKANOLS Montedison S.p.A. (IT) 1992-06-17 EP disclosed
EP-0222561-B1 PROCESS FOR ENZYMATIC SEPARATION OF OPTICAL ISOMERS OF 2-AMINOBUTANOL Montedison S.p.A. (IT) 1991-05-08 EP disclosed
US-4792616-A Diaryl ethers HOFFMANN-LA ROCHE INC. (US) 1988-12-20 US disclosed
EP-0239122-A2 Process for the enzymatic resolution of racemic 2-amino-1-alkanols Montedison S.p.A. (IT) 1987-09-30 EP disclosed
EP-0222561-A2 Process for enzymatic separation of optical isomers of 2-aminobutanol Montedison S.p.A. (IT) 1987-05-20 EP disclosed
US-4582526-A Carbamic acid ester herbicides HOFFMANN-LA ROCHE INC. (US) 1986-04-15 US disclosed