Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17147756 | 0.75 | DUSP3 (0.47) | DUSP3TYRALDH1A1ALOX12 | |
| SCHEMBL9638587 | 0.67 | ALDH1A1 (0.40) | KDM4EALDH1A1MAOB | |
| SCHEMBL702562 | 0.66 | — | — | |
| SCHEMBL27168868 | 0.65 | TRIM24 (0.30) | KDM4EALDH1A1 | |
| SCHEMBL6793523 | 0.65 | ALDH1A1 (0.33) | KDM4EALDH1A1MAOAMAOB | |
| SCHEMBL14194458 | 0.63 | ALDH1A1 (0.48) | DUSP3ALDH1A1MAOAMAOB | |
| SCHEMBL6481220 | 0.59 | CDC25B (0.54) | KDM4EALDH1A1ALOX12MAOA | |
| SCHEMBL28165669 | 0.58 | — | — | |
| Methyl Alcohol SCHEMBL28318378 | 0.56 | MAOA (0.87) | KDM4EALDH1A1ALOX12MAOAMAOB | |
| SCHEMBL13934162 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153218-A | N,N',N'-trisubstituted-bis-amino-3-methylene-2,4(3H,5H)-furandione inhibitors of acyl-CoA:cholesterol-acyl transferase | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |