Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 16/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638150 | 0.87 | ABCB11 (0.37) | — | |
| SCHEMBL844427 | 0.75 | ABCB11 (0.38) | — | |
| SCHEMBL9197021 | 0.73 | PARP1 (0.33) | DHODHPARP1 | |
| SCHEMBL4119807 | 0.72 | DHODH (0.44) | DHODHPARP1CMKLR1 | |
| SCHEMBL7972086 | 0.70 | CMKLR1 (0.35) | CMKLR1 | |
| SCHEMBL8866651 | 0.69 | DHODH (0.44) | DHODH | |
| SCHEMBL9291479 | 0.69 | PARP1 (0.35) | PARP1 | |
| SCHEMBL8836872 | 0.69 | BRS3 (0.33) | — | |
| SCHEMBL4373827 | 0.69 | ABCB11 (0.55) | — | |
| SCHEMBL1775436 | 0.68 | AGTR1 (0.38) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128356-A | Angiotensin antagonist; cardiovascular disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-07 | — | — | US | disclosed |