Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | GMNN | O75496 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638704 | 1.00 | LMNA (0.40) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9744611 | 0.87 | HDAC3 (0.42) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11101582 | 0.85 | HDAC3 (0.38) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15519768 | 0.80 | ALDH1A1 (0.48) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL27830247 | 0.80 | ALDH1A1 (0.40) | LMNAMAPK1MAPTALDH1A1CYP1A2 | |
| SCHEMBL9657353 | 0.78 | CYP2D6 (0.41) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9657356 | 0.78 | CYP2D6 (0.41) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9743287 | 0.77 | MAPK1 (0.47) | LMNAMAPK1MAPTALDH1A1CYP2D6 | |
| SCHEMBL9745613 | 0.76 | MAPK1 (0.54) | LMNAMAPK1MAPTALDH1A1CYP2D6 | |
| SCHEMBL9743364 | 0.76 | MAPK1 (0.54) | LMNAMAPK1MAPTALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288994-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | Chisso Corporation (JP) | 1992-07-22 | — | — | EP | disclosed |
| US-4962031-A | SPECIFIC COMPOUNDS HAVING HYDROXYL GROUPS REACTED WITH ESTERS IN PRESENCE OF HYDROLASES | CHISSO CORPORATION (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0288994-A2 | Process for producing optically active compounds | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |