Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657356 | 1.00 | CYP2D6 (0.41) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28611085 | 0.87 | LMNA (0.57) | CYP2D6LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL28611084 | 0.87 | LMNA (0.57) | CYP2D6LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL9744611 | 0.81 | HDAC3 (0.42) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL34471491 | 0.80 | CYP2D6 (0.45) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27929482 | 0.79 | TSHR (0.44) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11101582 | 0.79 | HDAC3 (0.38) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9638704 | 0.78 | LMNA (0.40) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9638709 | 0.78 | LMNA (0.40) | CYP2D6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10446 | 0.78 | ALDH1A1 (0.55) | CYP2D6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266217-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | CHISSO CORPORATION (JP) | 1992-12-30 | — | — | EP | disclosed |
| US-4916074-A | ENZYMATIC TRANS ESTERIFICATION OF ALCOHOL WITH TRIGLYCERIDES; PSEUDOMONAS-DERIVED ENZYME | CHISSO CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0266217-A2 | Process for producing optically active compounds | CHISSO CORPORATION (JP) | 1988-05-04 | — | — | EP | disclosed |