Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.30 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.30 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624729 | 0.72 | ACHE (0.39) | ALDH1A1TAS1R3TAS1R1TDP1ACHE | |
| SCHEMBL12325397 | 0.72 | ACHE (0.39) | ALDH1A1TDP1ACHETUBB4ATUBB | |
| SCHEMBL14337804 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TAS1R3TAS1R1TDP1ACHE | |
| SCHEMBL6413134 | 0.69 | ALDH1A1 (0.40) | ALDH1A1TAS1R3TAS1R1TDP1ACHE | |
| SCHEMBL14337807 | 0.65 | ALDH1A1 (0.38) | ALDH1A1TAS1R3TAS1R1ACHESRC | |
| SCHEMBL12504651 | 0.65 | SCN4A (0.44) | ALDH1A1TDP1ACHE | |
| SCHEMBL10030804 | 0.64 | ACHE (0.43) | ALDH1A1TDP1ACHE | |
| SCHEMBL129762 | 0.64 | ACHE (0.57) | ALDH1A1TDP1ACHETUBB4ATUBB | |
| SCHEMBL14700548 | 0.63 | HTT (0.42) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2955343 | 0.62 | ALDH1A1 (0.56) | ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081272-A | PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4056581-A | Process for the preparation of phosphorodichloridothiolates | ROHM AND HAAS COMPANY (US) | 1977-11-01 | — | — | US | disclosed |