Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339727 | 0.76 | TSHR (0.39) | TSHR | |
| SCHEMBL9638454 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL5376527 | 0.75 | TSHR (0.41) | TSHR | |
| SCHEMBL6557963 | 0.67 | TSHR (0.48) | TSHR | |
| SCHEMBL7627471 | 0.65 | TSHR (0.46) | TSHR | |
| SCHEMBL9126560 | 0.64 | SLC6A3 (0.31) | — | |
| SCHEMBL6596963 | 0.63 | TSHR (1.00) | TSHR | |
| SCHEMBL4791985 | 0.62 | TSHR (0.43) | TSHR | |
| Adamantane SCHEMBL6037700 | 0.61 | TSHR (0.46) | TSHR | |
| SCHEMBL1072862 | 0.60 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246114-B1 | PHOTOCHROMIC SPIROPYRAN COMPOUNDS | GEC-MARCONI LIMITED (GB) | 1992-09-02 | — | — | EP | disclosed |
| US-4826977-A | Photochromic spiropyran compounds | THE PLESSEY COMPANY PLC (GB) | 1989-05-02 | — | — | US | disclosed |
| EP-0246114-A2 | Photochromic spiropyran compounds | GEC-MARCONI LIMITED (GB) | 1987-11-19 | — | — | EP | disclosed |