Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404659 | 0.82 | TP53 (0.38) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL207843 | 0.81 | MAPT (0.39) | ALDH1A1LMNAMAPTPPM1BPTPN1 | |
| SCHEMBL3108344 | 0.79 | MEN1 (0.41) | ALDH1A1LMNATP53MAPTPOLB | |
| SCHEMBL16104755 | 0.76 | MAPT (0.41) | ALDH1A1KDM4EUSP2LMNAMMP9 | |
| SCHEMBL5003310 | 0.76 | GAA (0.39) | ALDH1A1LMNATSHRMAPTPOLB | |
| SCHEMBL5003314 | 0.76 | GAA (0.39) | ALDH1A1LMNATSHRMAPTPOLB | |
| SCHEMBL9961300 | 0.75 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL6402662 | 0.75 | MAPT (0.38) | ALDH1A1MAPTPOLBPPM1BPTPN1 | |
| SCHEMBL4441643 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL879299 | 0.74 | ALDH1A1 (0.39) | ALDH1A1LMNATSHRTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269514-B1 | DERIVATIVES OF 2,2-DIMETHYLCYCLOPROPANECARBOXYLIC ACID BEARING A SATURATED HALOGENATED CHAIN AT C-3, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-08-26 | — | — | EP | disclosed |