Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14782916 | 0.88 | GABRA1 (0.38) | TP53MAPTALDH1A1POLBKMT2A | |
| SCHEMBL9638879 | 0.82 | ALDH1A1 (0.41) | TP53MAPTALDH1A1POLBKMT2A | |
| SCHEMBL27498733 | 0.74 | — | — | |
| SCHEMBL3108344 | 0.73 | MEN1 (0.41) | TP53MAPTALDH1A1POLBKMT2A | |
| SCHEMBL27752052 | 0.72 | ALDH1A1 (0.39) | MAPTALDH1A1LMNATSHR | |
| SCHEMBL1307950 | 0.72 | MAPT (0.46) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL5006280 | 0.72 | MAPT (0.46) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL28683614 | 0.72 | TP53 (0.44) | TP53KMT2ASMN1; SMN2PKMUSP2 | |
| SCHEMBL15426657 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL16104755 | 0.71 | MAPT (0.41) | TP53MAPTALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340484-A | Benzyloxy indole branched-chain acid derivative and its preparation method and use | 上海美迪西生物医药股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-111278809-A | Bicyclic sulfones and sulfoxides, and methods of use thereof | 豪夫迈·罗氏有限公司 | 2020-06-12 | — | — | CN | disclosed |