Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5933416 | 0.94 | CA2 (0.39) | TSHRUSP2CA2CA1TDP1 | |
| SCHEMBL2773032 | 0.87 | TSHR (0.53) | TSHRUSP2CA2CA1TDP1 | |
| Methanesulfonic Acid Methyl Ester SCHEMBL29808761 | 0.85 | USP2 (0.62) | TSHRUSP2CA2CA1 | |
| Propane SCHEMBL2200005 | 0.84 | — | — | |
| SCHEMBL1043227 | 0.84 | CA2 (0.44) | TSHRCA2CA1TDP1CA12 | |
| Propane SCHEMBL16671226 | 0.81 | CA2 (0.39) | TSHRUSP2CA2CA1TDP1 | |
| Alcohol SCHEMBL27553856 | 0.81 | — | — | |
| SCHEMBL6761796 | 0.81 | TSHR (0.53) | TSHRUSP2CA2CA1TDP1 | |
| Sulfuric Acid SCHEMBL6727151 | 0.81 | CA5A (0.46) | TSHRCA2CA1TDP1CA7 | |
| SCHEMBL8591036 | 0.81 | TSHR (0.53) | TSHRUSP2CA2CA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227358-B1 | HOUSING PACK FOR PHOTOGRAPHIC PROCESSING SOLUTION | KONICA CORPORATION (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-4791013-A | STORAGE AND WASTE COMPARTMENTS; OXYGEN BARRIER MEMBRANE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0227358-A2 | Housing pack for photographic processing solution | KONICA CORPORATION (JP) | 1987-07-01 | — | — | EP | disclosed |