⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL895300 | 0.97 | CYP1A2 (0.55) | — | |
| SCHEMBL8158436 | 0.97 | CYP1A2 (0.55) | — | |
| SCHEMBL22815615 | 0.92 | RAB9A (0.52) | — | |
| SCHEMBL4638703 | 0.85 | SLC6A4 (0.54) | — | |
| SCHEMBL27159383 | 0.85 | RAB9A (0.47) | — | |
| SCHEMBL28605254 | 0.85 | CYP1A2 (0.61) | — | |
| Methane SCHEMBL11477836 | 0.83 | MEN1 (0.46) | — | |
| Ethane SCHEMBL10983230 | 0.83 | MEN1 (0.46) | — | |
| SCHEMBL11865454 | 0.83 | MEN1 (0.46) | — | |
| SCHEMBL83839 | 0.83 | ALDH1A1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2617 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | claimed |
| CN-112410312-A | Cyclohexanone monooxygenase and application thereof | 江南大学 | 2021-02-26 | — | — | CN | claimed |
| CN-109791140-A | The system and method for difference diagnosis for disease | 泰克年研究发展基金会公司 | 2019-05-21 | — | — | CN | claimed |
| CN-106631941-B | A kind of preparation method of -3 chlorphenyl methyl sulfide of 2- methyl | 青岛瀚生生物科技股份有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-106631941-A | Preparation method of 2-methyl-3-chlorophenylmethyl sulfide | 青岛瀚生生物科技股份有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104058911-B | A kind of method utilizing micro passage reaction to prepare sulfoxide or sulfone | 联化科技股份有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-103910658-A | Method of oxidizing thioether to sulfone | UNIV NINGXIA | 2014-07-09 | — | — | CN | claimed |
| WO-2012074912-A1 | METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-06-07 | — | — | WO | claimed |
| EP-1879567-A1 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-01-23 | — | — | EP | claimed |
| US-20060247291-A1 | Amino acid derivatives | PFIZER, INC. | 2006-11-02 | — | — | US | claimed |
| WO-2006114707-A1 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-02 | — | — | WO | claimed |
| US-20040230077-A1 | Method of producing optically active sulfimide compound | KYUSHU UNIVERSITY (JP) | 2004-11-18 | — | — | US | claimed |
| EP-1452523-A2 | Method of producing optically active sulfimide compounds | KYUSHU UNIVERSITY (JP) | 2004-09-01 | — | — | EP | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| EP-0573604-B1 | METHODS FOR THE TREATMENT OF OSTEOPOROSIS | PROCTER & GAMBLE PHARMA (US) | 1995-03-15 | — | — | EP | claimed |
| WO-1992012983-A1 | A METHOD OF FLUORINATING BY USING N-FLUOROPYRIDINIUM PYRIDINE HEPTAFLUORODIBORATE | ALLIED-SIGNAL INC. (US) | 1992-08-06 | — | — | WO | claimed |
| US-5047544-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | claimed |
| US-5036073-A | For agricultural use | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-30 | — | — | US | claimed |
| US-4495365-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL CO. (US) | 1985-01-22 | — | — | US | claimed |
| US-4293701-A | N-(Benzenesulfonyl) carbamates - herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-10-06 | — | — | US | claimed |