Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774995 | 0.88 | CYP1A1 (0.52) | SLC6A4SLC6A2SLC6A3MAOBCYP1A2 | |
| SCHEMBL27458776 | 0.86 | MAOA (0.56) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| Methylsulfanylmethane SCHEMBL27435778 | 0.85 | MAOA (0.61) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL96393 | 0.85 | — | — | |
| SCHEMBL3671853 | 0.83 | HSPB1 (0.51) | SLC6A4SLC6A2SLC6A3CYP1A2MEN1 | |
| SCHEMBL8158436 | 0.83 | CYP1A2 (0.55) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| Fluoride SCHEMBL895300 | 0.83 | CYP1A2 (0.55) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL943600 | 0.81 | MAOA (0.56) | MAOAMAOBCYP1A2MEN1KMT2A | |
| SCHEMBL9242729 | 0.80 | MAOA (0.74) | MAOAMAOBCYP1A2MEN1KMT2A | |
| SCHEMBL457634 | 0.80 | MAOA (0.74) | MAOAMAOBCYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357109-B1 | Process for aryl alkyl sulfide | HOFFMANN LA ROCHE (CH) | 2008-07-23 | — | — | EP | claimed |
| CN-1160326-C | Process for prodcing 3-aryl sulfate iso-hydroximic acid | - | 2004-08-04 | — | — | CN | claimed |
| EP-1357109-A2 | Process for aryl alkyl sulfide | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-29 | — | — | EP | claimed |
| US-20020133030-A1 | Processes for preparing 3-arylsulfur hydroxamic acids | SYNTEX USA, LLC (US) | 2002-09-19 | — | — | US | claimed |
| US-20020038037-A1 | Processes for preparing 3-arylsulfur hydroxamic acids | SYNTEX (U.S.A.) INC. (US) | 2002-03-28 | — | — | US | claimed |
| US-6342639-B1 | ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES | SYNTEX (U.S.A.) LLC | 2002-01-29 | — | — | US | claimed |
| EP-0965592-A1 | Process for preparing 3-arylsulfur hydroxamic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-22 | — | — | EP | claimed |
| CN-1160326-C | Process for prodcing 3-aryl sulfate iso-hydroximic acid | - | 2004-08-04 | — | — | CN | disclosed |
| CN-1101809-C | Process for preparing 3-arylsulfur hydroxamic acids | HOFFMANN LA ROCHE (CH) | 2003-02-19 | — | — | CN | disclosed |
| US-6518460-B2 | Antiinflammatory agents; cardiovascular disorders | SYNTEX (U.S.A.) LLC | 2003-02-11 | — | — | US | disclosed |
| US-20020133030-A1 | Processes for preparing 3-arylsulfur hydroxamic acids | SYNTEX USA, LLC (US) | 2002-09-19 | — | — | US | disclosed |
| US-6420573-B1 | ALKYLATING A COMPOUND OF FORMULA II, RO-C( HORIZONTAL-LINE O)-CH(R1)(R2), WHERE R IS ALKYL OR HYDROGEN, WITH AN ARYLMETHYLTHIO COMOPUND; REPLACING GROUP RO-WITH XONX- AND OXIDIZING | SYNTEX (U.S.A.) LLP | 2002-07-16 | — | — | US | disclosed |
| US-20020038037-A1 | Processes for preparing 3-arylsulfur hydroxamic acids | SYNTEX (U.S.A.) INC. (US) | 2002-03-28 | — | — | US | disclosed |
| US-6342639-B1 | ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES | SYNTEX (U.S.A.) LLC | 2002-01-29 | — | — | US | disclosed |
| WO-2001062720-A1 | METHOD FOR PRODUCING 1-CHLORO-4-[4-(ALKYLTHIO)PHENOXY]-BENZENES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038037-A1 | Processes for preparing 3-arylsulfur hydroxamic acids | HAX1, ARSA, PRDX1 | SLC6A4 3075/4885SLC6A2 4071/4885SLC6A3 3480/4885 |
| US-20020133030-A1 | Processes for preparing 3-arylsulfur hydroxamic acids | HAX1, ARSA, PRDX1 | SLC6A4 3075/4885SLC6A2 4071/4885SLC6A3 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.