Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640825 | 0.90 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8752479 | 0.80 | CYP2C19 (0.53) | KDM4EALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL9641124 | 0.79 | KMT2A (0.43) | KDM4EHSD17B10ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7085464 | 0.78 | CYP2C19 (0.41) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7089037 | 0.78 | KMT2A (0.55) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7220888 | 0.77 | MAPK1 (0.61) | KDM4EALDH1A1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7085041 | 0.76 | KMT2A (0.50) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9640865 | 0.76 | OR51E2 (0.47) | KDM4EALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6750019 | 0.76 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL31102464 | 0.76 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339411-B1 | PROCESS FOR THE PREPARATION OF QUINOXALONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0339411-A1 | Process for the preparation of quinoxalones | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | disclosed |