Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640825 | 0.82 | KDM4E (0.61) | PKMKMT2AMEN1LMNATSHR | |
| SCHEMBL9641124 | 0.82 | KMT2A (0.43) | PKMKMT2AMEN1LMNAHTT | |
| SCHEMBL4480930 | 0.81 | OR51E2 (0.54) | OR51E2HSD17B1HSD17B2PKMKMT2A | |
| SCHEMBL10912278 | 0.79 | MEN1 (0.55) | KMT2AMEN1LMNATSHRHTT | |
| SCHEMBL1026559 | 0.78 | ALDH1A1 (0.59) | OR51E2HSD17B1HSD17B2PKMKMT2A | |
| SCHEMBL9639889 | 0.78 | CYP1A2 (0.48) | PKMKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL7089035 | 0.78 | MAPK1 (0.51) | PKMLMNAHTTNPC1RAB9A | |
| SCHEMBL8752479 | 0.77 | CYP2C19 (0.53) | PKMLMNAHTTNPC1RAB9A | |
| SCHEMBL20556460 | 0.77 | OR51E2 (0.75) | OR51E2HSD17B1HSD17B2LMNATSHR | |
| SCHEMBL11374252 | 0.77 | MAPT (0.62) | HSD17B1HSD17B2PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339411-B1 | PROCESS FOR THE PREPARATION OF QUINOXALONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0339411-A1 | Process for the preparation of quinoxalones | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-02 | — | — | EP | disclosed |